DUREZOL PRESCRIBING INFORMATION PDF

The treatment of endogenous anterior uveitis. Dosage and Administration For the treatment of inflammation and pain associated with ocular surgery instill one drop into the conjunctival sac of the affected eye 4 times daily beginning 24 hours after surgery and continuing throughout the first 2 weeks of the postoperative period, followed by 2 times daily for a week and then a taper based on the response. For the treatment of endogenous anterior uveitis, instill one drop into the conjunctival sac of the affected eye 4 times daily for 14 days followed by tapering as clinically indicated. Warnings and Precautions Intraocular pressure IOP increase — Prolonged use of corticosteroids may result in glaucoma with damage to the optic nerve, defects in visual acuity and fields of vision.

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The treatment of endogenous anterior uveitis. Dosage and Administration For the treatment of inflammation and pain associated with ocular surgery instill one drop into the conjunctival sac of the affected eye 4 times daily beginning 24 hours after surgery and continuing throughout the first 2 weeks of the postoperative period, followed by 2 times daily for a week and then a taper based on the response. For the treatment of endogenous anterior uveitis, instill one drop into the conjunctival sac of the affected eye 4 times daily for 14 days followed by tapering as clinically indicated.

Warnings and Precautions Intraocular pressure IOP increase — Prolonged use of corticosteroids may result in glaucoma with damage to the optic nerve, defects in visual acuity and fields of vision. If this product is used for 10 days or longer, IOP should be monitored. Cataracts — Use of corticosteroids may result in posterior subcapsular cataract formation. Delayed healing — The use of steroids after cataract surgery may delay healing and increase the incidence of bleb formation.

In those diseases causing thinning of the cornea or sclera, perforations have been known to occur with the use of topical steroids. The initial prescription and renewal of the medication order beyond 28 days should be made by a physician only after examination of the patient with the aid of magnification such as slit lamp biomicroscopy and, where appropriate, fluorescein staining. Bacterial infections — Prolonged use of corticosteroids may suppress the host response and thus increase the hazard of secondary ocular infections.

In acute purulent conditions, steroids may mask infection or enhance existing infection. Viral infections — Employment of a corticosteroid medication in the treatment of patients with a history of herpes simplex requires great caution.

Use of ocular steroids may prolong the course and may exacerbate the severity of many viral infections of the eye including herpes simplex. Fungus invasion must be considered in any persistent corneal ulceration where a steroid has been used or is in use. References: 1. Durezol [package insert]. Stringer W, Bryant R. Dose uniformity of topical corticosteroid preparations: difluprednate ophthalmic emulsion 0.

Clin Ophthalmol.

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One Therapy With Many Features

Endogenous Anterior Uveitis Durezol is also indicated for the treatment of endogenous anterior uveitis. Durezol Dosage and Administration Ocular Surgery Instill one drop into the conjunctival sac of the affected eye 4 times daily beginning 24 hours after surgery and continuing throughout the first 2 weeks of the postoperative period, followed by 2 times daily for a week and then a taper based on the response. Endogenous Anterior Uveitis Instill one drop into the conjunctival sac of the affected eye 4 times daily for 14 days followed by tapering as clinically indicated. Dosage Forms and Strengths Durezol contains 0. Contraindications The use of Durezol, as with other ophthalmic corticosteroids, is contraindicated in most active viral diseases of the cornea and conjunctiva including epithelial herpes simplex keratitis dendritic keratitis , vaccinia, and varicella, and also in mycobacterial infection of the eye and fungal disease of ocular structures. Warnings and Precautions Intraocular pressure IOP Increase Prolonged use of corticosteroids may result in glaucoma with damage to the optic nerve, defects in visual acuity and fields of vision. Steroids should be used with caution in the presence of glaucoma.

ASTM D5236 PDF

One Therapy for Many Eyes

The treatment of endogenous anterior uveitis. Dosage and Administration For the treatment of inflammation and pain associated with ocular surgery instill one drop into the conjunctival sac of the affected eye 4 times daily beginning 24 hours after surgery and continuing throughout the first 2 weeks of the postoperative period, followed by 2 times daily for a week and then a taper based on the response. For the treatment of endogenous anterior uveitis, instill one drop into the conjunctival sac of the affected eye 4 times daily for 14 days followed by tapering as clinically indicated. Warnings and Precautions Intraocular pressure IOP increase — Prolonged use of corticosteroids may result in glaucoma with damage to the optic nerve, defects in visual acuity and fields of vision. If this product is used for 10 days or longer, IOP should be monitored. Cataracts — Use of corticosteroids may result in posterior subcapsular cataract formation.

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